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Everlywell vs. LetsGetChecked vs. Quest: Best At-Home Hormone & Health Tests Compared
Which kit measures what, how the sample is collected, and where at-home testing stops being useful for women and men over 40.
Reviewed against NIH & PubMed research. By HealthSpan40 Editorial Team · Last updated October 10, 2026.
ⓘ Pending expert review: This guide was written and cited from published research as a reference starting point. It has not yet been reviewed by a credentialed medical professional. Treat it as background reading, not clinical guidance.
Somewhere after 40, many people start wondering whether a hormone or thyroid problem is behind their tiredness, poor sleep, weight changes, low drive or hot flashes. Ordering a test online is easy, and the three best-known options are Everlywell, LetsGetChecked and Quest. They look similar on the surface, but they differ in what each test measures, how you give the sample, and how clearly the company publishes prices and lab details.
This guide compares the tests most relevant to adults over 40: perimenopause hormone panels for women, thyroid panels for both sexes, and testosterone tests for men. It also explains what these tests cannot tell you, because that matters more than which brand you pick. We compared the companies’ published product pages and the current clinical guidance. We did not personally order or run these kits, and where a page did not state a price or detail, we say so rather than guess.
Our top picks at a glance
Quest (questhealth.com)
Published prices for thyroid, men’s and women’s panels, with lab visit, in-home phlebotomist or at-home kit.
Everlywell Thyroid Test
Finger-prick TSH, Free T3, Free T4 and TPO antibodies at about $149, with physician review.
LetsGetChecked Female Hormone Test
Finger-prick FSH, LH, prolactin and estradiol, with results in about 2 to 5 days.
Quick comparison
| Test | Best for | Measures | Sample | Approx. price* | |
|---|---|---|---|---|---|
| Quest Women’s Hormone Panel, Expanded | Broad women’s panel | More than 10 hormones | Lab visit, in-home draw or kit | about $289 | View |
| Quest Men’s Hormone Panel, Expanded | Men’s testosterone panel | Testosterone plus four related markers | Lab visit, in-home draw or kit | about $220 | View |
| Everlywell Thyroid Test | Thyroid screening | TSH, Free T3, Free T4, TPO antibodies | Finger prick | about $149 | View |
| Everlywell Perimenopause Test | Hormone snapshot | Estradiol, LH, FSH | Finger prick (day 3 of cycle) | Not listed on page | View |
| LetsGetChecked Female Hormone Test | Focused hormone panel | FSH, LH, prolactin, estradiol | Finger prick | Not listed on page | View |
| LetsGetChecked Testosterone Test | Men’s single marker | Testosterone | Finger prick | Not listed on page | View |
*Prices at time of writing; check the retailer for current pricing. Where a product page did not list a price, we did not estimate one.
How we chose
We focused on tests that match common questions in midlife: perimenopause and menopause for women, thyroid function for both sexes, and testosterone for men. We compared:
- Which biomarkers each test reports
- How the sample is collected (finger prick, lab draw or in-home phlebotomist)
- Published pricing
- Whether the company states it uses CLIA-certified laboratories
- Whether a clinician reviews results or follows up
- How clearly the page states what the test can and cannot show
The best at-home hormone and health tests for adults over 40
Quest Health hormone and thyroid panels
Quest’s consumer site lists several panels with prices on the page. The Comprehensive Thyroid Test Panel is about $149 and covers TSH, Free T3, Free T4 and two thyroid antibodies. The Men’s Hormone Test Panel, Expanded is about $220 and measures testosterone plus four related markers. The Women’s Hormone Test Panel, Expanded is about $289 and covers more than 10 hormones. The page does not name a menopause-specific test, so the women’s panel is the closest match.
The collection options are the main advantage. You can buy a test, register it and visit one of more than 2,000 Quest locations; add in-home collection by a mobile phlebotomist for about $79 (availability varies by area); or, for some tests, use an at-home kit. The page does not say which method each test supports, so check the product page before buying. Quest states that Quest Diagnostics and certain affiliates are CLIA-certified laboratories. Note that the consumer website is operated by a separate Quest entity that does not provide HIPAA-covered services, which is worth reading in the privacy terms.
Pros
- Prices shown on the page
- Venous blood draw option, which many clinicians prefer for hormones
- Large network of collection sites
Cons
- No menopause-specific panel named
- In-home draw costs extra
- Which collection options apply to which test is not stated on the overview page
Best for: people who want a clear price and a lab-quality blood draw. Skip if: you want a finger-prick kit with no appointment at all.
Everlywell Thyroid Test
Everlywell’s thyroid test measures four markers from a small finger-prick blood spot: TSH, Free T3, Free T4 and thyroid peroxidase (TPO) antibodies. The page says labs are CLIA-certified, results are typically in your account within a few days, and an independent board-certified physician in your state reviews them. FSA and HSA cards are accepted.
It is a reasonable first look for fatigue, feeling cold, constipation or other symptoms that overlap with thyroid problems, which become more common in midlife, especially in women. TSH is usually the first test a clinician orders, according to NIDDK, and an abnormal result needs follow-up. The trade-off is that a finger-prick sample is smaller than a standard blood draw, and the page does not name the lab.
Pros
- Covers TSH, both thyroid hormones and an antibody marker
- Physician review of results
- Price listed on the page
Cons
- Finger-prick sample
- Lab not named on the page
- Does not replace a clinician workup if abnormal
Best for: a convenient first thyroid screen. Skip if: you already have a thyroid diagnosis; your own clinician should manage monitoring.
Everlywell Perimenopause Test
This kit measures estradiol, luteinizing hormone (LH) and follicle-stimulating hormone (FSH) from a few drops of blood collected at home on day 3 of your cycle. The company describes it as a cost-effective starting point and says the lab is CLIA-certified. The page we read did not list a price or turnaround time.
The key limit is biological. During perimenopause, hormone levels swing from month to month and even day to day, and the timing instruction (day 3) only works if you still have periods. Mayo Clinic says there is no single test for perimenopause and that hormone testing usually does not establish it. A result can add a data point, but a normal result does not rule perimenopause out, and an abnormal one does not by itself tell you what to do.
Pros
- Simple at-home collection
- Measures the hormones clinicians most often discuss
Cons
- Single-time-point results in a fluctuating phase
- Requires a cycle to time correctly
- Price not shown on the page we read
Best for: women who want a baseline to bring to an appointment. Skip if: your periods have stopped or you are on hormonal birth control or hormone therapy, which can change results; ask your clinician first.
LetsGetChecked Female Hormone Test
LetsGetChecked’s female hormone test reports FSH, LH, prolactin and estradiol from a finger-prick blood sample collected at home with the supplied lancets and tube. Online results are available about two to five days after the lab receives the sample. The company says it has its own CLIA-certified laboratory and lists CAP accreditation, though the product page does not say which lab processes this particular test. FSA and HSA cards are accepted.
It shares the same limits as any single hormone snapshot in perimenopause, and the page did not list a price, so check the current price at checkout. Adding prolactin can be useful because high prolactin is one of several causes of irregular periods that a clinician may want to rule out.
Pros
- Includes prolactin along with FSH, LH and estradiol
- Company-owned CLIA-certified lab stated
- Stated 2 to 5 day results
Cons
- Price not shown on the product page
- Processing lab for this test not specified
- Same fluctuation limits as other snapshots
Best for: women who want a slightly broader reproductive panel from home. Skip if: you want a thyroid panel; the thyroid page we checked was listed as unavailable.
LetsGetChecked Testosterone Test
This test measures testosterone only, from a finger-prick sample collected at home. Results appear in a secure online account about two to five days after the lab receives the sample. Free shipping and FSA/HSA acceptance are listed; a price was not.
The American Urological Association’s guideline is clear that one number is not a diagnosis. It recommends two total testosterone measurements on separate mornings, ideally from the same lab and assay, and treats a level below 300 ng/dL as a reasonable cut-off only when paired with symptoms or signs. The guideline also warns that symptoms such as fatigue are nonspecific and can reflect stress, depression or other conditions. A single afternoon sample from a kit can mislead, so collect in the morning as instructed and bring the result to a clinician.
Pros
- Easy first look at total testosterone
- Results online within days of lab receipt
Cons
- Single marker, no context from related hormones
- One test does not meet guideline diagnostic criteria
- Price not shown on the page
Best for: men who want a baseline before seeing a clinician. Skip if: you want a broader panel; Quest’s expanded men’s panel adds four related markers.
Other options
Everlywell also lists a total testosterone test for men; its page did not state a price or sample method, so we did not review it in depth. Our earlier roundup of at-home hormone test kits covers more of the field.
Buying guide: what matters after 40
Match the test to the question
If your main concern is fatigue, weight change or feeling cold, a thyroid panel is the most useful of these tests, because thyroid disease is common and treatable. If you are a woman with irregular periods and hot flashes, a hormone panel may add context, but the diagnosis rests on symptoms and age. If you are a man with low drive or low energy, testosterone is only meaningful when measured properly and read alongside symptoms.
Finger prick versus venous draw
Finger-prick kits are convenient but use a small sample that can be harder to collect well. A venous blood draw at a lab or from a mobile phlebotomist is the standard clinical method. Quest offers both routes; Everlywell and LetsGetChecked product pages we read describe finger-prick collection. Follow the timing instructions exactly, including fasting, morning collection or cycle day, because they change the result.
What CLIA certification means
CLIA is the federal program, run by the Centers for Medicare & Medicaid Services, that sets quality standards for human laboratory testing in the United States. A CLIA-certified lab has met those standards, but certification does not tell you whether a particular test is the right one for your question or whether its results will be interpreted well. Each company says it uses CLIA-certified labs; we did not independently verify individual certificates.
Interpretation and follow-up
Check whether a clinician reviews your result and whether you can talk to one. Everlywell says an independent physician in your state reviews thyroid results. Whatever the brand, take abnormal results to your own doctor, who can repeat the test, check related markers and consider your medications. Biotin supplements, birth control, hormone therapy, steroids and recent illness can all alter results.
Privacy
Hormone and health data are sensitive. Read how each company stores and shares results, and note that Quest’s consumer site is operated by an affiliate that, per Quest, does not provide HIPAA-covered services.
What the research says
Guidance from major medical sources points the same way. Mayo Clinic notes that perimenopause has no single diagnostic test, that blood tests play a limited role, and that hormone levels fluctuate erratically; thyroid testing is the main exception because thyroid problems can mimic or worsen menopausal symptoms. NIDDK says clinicians usually check TSH first, add free T4 and sometimes T3, and order antibody tests when results suggest thyroid disease. An abnormal TSH calls for at least one more test to find the cause.
For men, the American Urological Association guideline recommends two early-morning total testosterone measurements and a level below 300 ng/dL as a reasonable threshold, with diagnosis requiring symptoms or signs as well. The FDA’s page on direct-to-consumer tests adds a general caution: these tests are not a substitute for a traditional health care evaluation, accuracy varies, a negative result does not always rule out a condition, and you should discuss results with a provider before making health decisions.
We found no independent head-to-head studies comparing the accuracy of these three companies’ hormone kits, so we cannot rank them on accuracy.
Frequently asked questions
Can an at-home test tell me if I am in menopause?
Not reliably. Hormone levels fluctuate in perimenopause, and clinicians usually diagnose based on age, symptoms and menstrual history. A test can add context but rarely settles the question.
Are at-home tests accurate?
Accuracy varies by test and by how well the sample is collected. Labs used by these companies state CLIA certification, but the FDA notes that test accuracy varies and that results should be discussed with a provider.
Which test should I start with if I am tired all the time?
A thyroid panel is a common starting point, along with a visit to a clinician who can also check blood count, vitamin levels and sleep. Fatigue has many causes.
Is one low testosterone result enough to start treatment?
No. The AUA guideline calls for two early-morning measurements and symptoms or signs before diagnosing testosterone deficiency.
Will insurance cover these tests?
Usually not. Several brands accept FSA and HSA cards. If your doctor orders the same tests, insurance may cover them, so compare before paying out of pocket.
When should I see a doctor instead of testing at home?
See a clinician for heavy or unusual bleeding, bleeding after menopause, chest pain, rapid heartbeat, severe depression, unexplained weight loss, a lump in the neck, or symptoms that interfere with daily life.
Related guides
Sources
- Quest Health — official site
- Everlywell Thyroid Test — Everlywell
- Everlywell Perimenopause Test — Everlywell
- Female Hormone Test — LetsGetChecked
- Testosterone Test — LetsGetChecked
- Perimenopause: diagnosis and treatment — Mayo Clinic
- Thyroid tests — NIDDK
- Testosterone Deficiency Guideline — American Urological Association
- Clinical Laboratory Improvement Amendments — CMS
- Direct-to-Consumer Tests — FDA
ⓘ Medical disclaimer: This guide is for educational purposes only and is not medical advice. At-home tests are screening tools and cannot diagnose menopause, thyroid disease or low testosterone on their own. Do not start, stop or change any medication based on a home test result. Talk to your doctor before starting supplements, devices or treatments.